Pharmacogenomic data analysis and interpretation

2016/06/23

2015 KSCPT 추계학술대회

Pharmacogenomic data analysis and interpretation

인제의대 약물유전체연구센터

과거자료

Tamox -(CYP2D6)-> Z-4 hydroxy Tamoxifen N-desmethyl-tamoxifen -(CYP2D6)-> endoxifen

Clinical benefit CYP2D6*10/*10 Genotype이 treatment effect에 영향을 미친다. Shorter TTP in patients with CYP2D6*10/*10 than those with the other genotypes