2016 ACREP

2016/06/24

ACREP

Observational Study

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Observational Study의 Pitfall 및 이를 극복하기 위한 방법

Experimental study? Yes

Randomized design? (interventional)- No

Randomized design? (interventional)- Yes

Experimental study? No

Comparison group? No = Observational study

Comparison group? Yes = Analytical study

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Conclusion

Diagnostic test & Biomarker Study

Contents - Diagnostic test

Contents - Biomarker

2차 자료원을 이용한 역학 연구군

대규모 이차 자료원을 이용한 clinical prediction model : individual risk/outcome probability 예측 분석법

| | linear reg | logi reg| Cox reg| |-|-|-|-| |Overall perf| R2 | Nagelkerke r2, brir|the same| |discrimination ability||C concordance stat(AUC)|Harell C stat, time-dependent AUC| |Calibratrion|Calibration plot, slope|the same+hosmer-lemeshow|the same|

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Contents